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A Fasting Insulin–Raising Allele at IGF1 Locus Is Associated with Circulating Levels of IGF-1 and Insulin Sensitivity

BACKGROUND: A meta-analysis of genome-wide data reported the discovery of the rs35767 polymorphism near IGF1 with genome-wide significant association with fasting insulin levels. However, it is unclear whether the effects of this polymorphism on fasting insulin are mediated by a reduced insulin sens...

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Detalles Bibliográficos
Autores principales: Mannino, Gaia Chiara, Greco, Annalisa, De Lorenzo, Carlo, Andreozzi, Francesco, Marini, Maria A., Perticone, Francesco, Sesti, Giorgio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877361/
https://www.ncbi.nlm.nih.gov/pubmed/24392014
http://dx.doi.org/10.1371/journal.pone.0085483