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Cerebral Ischemia Is Exacerbated by Extracellular Nicotinamide Phosphoribosyltransferase via a Non-Enzymatic Mechanism

Intracellular nicotinamide phosphoribosyltransferase (iNAMPT) in neuron has been known as a protective factor against cerebral ischemia through its enzymatic activity, but the role of central extracellular NAMPT (eNAMPT) is not clear. Here we show that eNAMPT protein level was elevated in the ischem...

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Detalles Bibliográficos
Autores principales: Zhao, Bing, Zhang, Meng, Han, Xue, Zhang, Xia-Yan, Xing, Qiong, Dong, Xu, Shi, Qiao-Juan, Huang, Peng, Lu, Yun-Bi, Wei, Er-Qing, Xia, Qiang, Zhang, Wei-Ping, Tang, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877362/
https://www.ncbi.nlm.nih.gov/pubmed/24392007
http://dx.doi.org/10.1371/journal.pone.0085403