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Effects of Baseline CSF α-Synuclein on Regional Brain Atrophy Rates in Healthy Elders, Mild Cognitive Impairment and Alzheimer’s Disease

BACKGROUND: Cerebrospinal fluid (CSF) α-synuclein is reduced in synucleinopathies, including dementia with Lewy bodies, and some studies have found increased CSF α-synuclein in Alzheimer’s disease (AD). No study has explored effects of CSF α-synuclein on brain atrophy. Here we tested if baseline CSF...

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Detalles Bibliográficos
Autores principales: Mattsson, Niklas, Insel, Philip, Tosun, Duygu, Zhang, Jing, Jack Jr, Clifford R., Galasko, Douglas, Weiner, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877372/
https://www.ncbi.nlm.nih.gov/pubmed/24392009
http://dx.doi.org/10.1371/journal.pone.0085443