Endocytosis of hERG Is Clathrin-Independent and Involves Arf6

The hERG potassium channel is critical for repolarisation of the cardiac action potential. Reduced expression of hERG at the plasma membrane, whether caused by hereditary mutations or drugs, results in long QT syndrome and increases the risk of ventricular arrhythmias. Thus, it is of fundamental imp...

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Detalles Bibliográficos
Autores principales: Karnik, Rucha, Ludlow, Melanie J., Abuarab, Nada, Smith, Andrew J., Hardy, Matthew E. L., Elliott, David J. S., Sivaprasadarao, Asipu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877390/
https://www.ncbi.nlm.nih.gov/pubmed/24392021
http://dx.doi.org/10.1371/journal.pone.0085630

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877390/
https://www.ncbi.nlm.nih.gov/pubmed/24392021
http://dx.doi.org/10.1371/journal.pone.0085630

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