Statistical Inference for Hardy-Weinberg Proportions in the Presence of Missing Genotype Information

In genetic association studies, tests for Hardy-Weinberg proportions are often employed as a quality control checking procedure. Missing genotypes are typically discarded prior to testing. In this paper we show that inference for Hardy-Weinberg proportions can be biased when missing values are disca...

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Detalles Bibliográficos
Autores principales: Graffelman, Jan, Sánchez, Milagros, Cook, Samantha, Moreno, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877411/
https://www.ncbi.nlm.nih.gov/pubmed/24391752
http://dx.doi.org/10.1371/journal.pone.0083316

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877411/
https://www.ncbi.nlm.nih.gov/pubmed/24391752
http://dx.doi.org/10.1371/journal.pone.0083316

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