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Statistical Inference for Hardy-Weinberg Proportions in the Presence of Missing Genotype Information
In genetic association studies, tests for Hardy-Weinberg proportions are often employed as a quality control checking procedure. Missing genotypes are typically discarded prior to testing. In this paper we show that inference for Hardy-Weinberg proportions can be biased when missing values are disca...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877411/ https://www.ncbi.nlm.nih.gov/pubmed/24391752 http://dx.doi.org/10.1371/journal.pone.0083316 |