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MicroRNA-494 Within an Oncogenic MicroRNA Megacluster Regulates G(1)/S Transition in Liver Tumorigenesis Through Suppression of Mutated in Colorectal Cancer

Hepatocellular carcinoma (HCC) is associated with poor survival for patients and few effective treatment options, raising the need for novel therapeutic strategies. MicroRNAs (miRNAs) play important roles in tumor development and show deregulated patterns of expression in HCC. Because of the liver’s...

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Detalles Bibliográficos
Autores principales: Lim, Lionel, Balakrishnan, Asha, Huskey, Noelle, Jones, Kirk D, Jodari, Mona, Ng, Raymond, Song, Guisheng, Riordan, Jesse, Anderton, Brittany, Cheung, Siu-Tim, Willenbring, Holger, Dupuy, Adam, Chen, Xin, Brown, David, Chang, Aaron N, Goga, Andrei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877416/
https://www.ncbi.nlm.nih.gov/pubmed/23913442
http://dx.doi.org/10.1002/hep.26662