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The drug-transporter gene MDR1 C3435T and G2677T/A polymorphisms and the risk of multidrug-resistant epilepsy in Turkish children

One-third of all individuals with epilepsy are resistant to antiepileptic drug (AED) treatment. Antiepileptic treatment response has been suggested to be modulated by genetic polymorphisms of drug efflux transporters. Several polymorphic variants within the multidrug resistance 1 (MDR1) gene, which...

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Detalles Bibliográficos
Autores principales: Seven, Mehmet, Batar, Bahadir, Unal, Selin, Yesil, Gozde, Yuksel, Adnan, Guven, Mehmet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877425/
https://www.ncbi.nlm.nih.gov/pubmed/24213830
http://dx.doi.org/10.1007/s11033-013-2866-y