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Caspase-2 promotes cytoskeleton protein degradation during apoptotic cell death

The caspase family of proteases cleaves large number of proteins resulting in major morphological and biochemical changes during apoptosis. Yet, only a few of these proteins have been reported to selectively cleaved by caspase-2. Numerous observations link caspase-2 to the disruption of the cytoskel...

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Detalles Bibliográficos
Autores principales: Vakifahmetoglu-Norberg, H, Norberg, E, Perdomo, A B, Olsson, M, Ciccosanti, F, Orrenius, S, Fimia, G M, Piacentini, M, Zhivotovsky, B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877538/
https://www.ncbi.nlm.nih.gov/pubmed/24309927
http://dx.doi.org/10.1038/cddis.2013.463