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ADAM17 is a survival factor for microglial cells in vitro and in vivo after spinal cord injury in mice

A disintegrin and metalloprotease 17 (ADAM17) is a sheddase with important substrates including tumor necrosis factor-α (TNF-α) and its receptors, the p75 neurotrophin receptor (p75NTR), and members of the epidermal growth factor family. The rationale of this study was to inhibit ADAM17-induced shed...

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Detalles Bibliográficos
Autores principales: Vidal, P M, Lemmens, E, Avila, A, Vangansewinkel, T, Chalaris, A, Rose-John, S, Hendrix, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877539/
https://www.ncbi.nlm.nih.gov/pubmed/24336074
http://dx.doi.org/10.1038/cddis.2013.466