Pin1 modulates p63α protein stability in regulation of cell survival, proliferation and tumor formation

The homolog of p53 gene, p63, encodes multiple p63 protein isoforms. TAp63 proteins contain an N-terminal transactivation domain similar to that of p53 and function as tumor suppressors; whereas ΔNp63 isoforms, which lack the intact N-terminal transactivation domain, are associated with human tumori...

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Detalles Bibliográficos
Autores principales: Li, C, Chang, D L, Yang, Z, Qi, J, Liu, R, He, H, Li, D, Xiao, Z X
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877541/
https://www.ncbi.nlm.nih.gov/pubmed/24309930
http://dx.doi.org/10.1038/cddis.2013.468

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877541/
https://www.ncbi.nlm.nih.gov/pubmed/24309930
http://dx.doi.org/10.1038/cddis.2013.468

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