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Cancer-derived immunoglobulin G promotes tumor cell growth and proliferation through inducing production of reactive oxygen species
Cancer cells have been found to express immunoglobulin G (IgG), but the exact functions and underlying mechanisms of cancer-derived IgG remain elusive. In this study, we first confirmed that downregulation of IgG restrained the growth and proliferation of cancer cells in vitro and in vivo. To elucid...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877547/ https://www.ncbi.nlm.nih.gov/pubmed/24309932 http://dx.doi.org/10.1038/cddis.2013.474 |