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Cystatin SN neutralizes the inhibitory effect of cystatin C on cathepsin B activity

Cystatin SN (CST1) is one of the several salivary cystatins that form tight equimolar complexes with cysteine proteases, such as the cathepsins. High expression of CST1 is correlated with advanced pTNM stage in gastric cancer. However, the functional role of CST1 in tumorigenesis has not been elucid...

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Detalles Bibliográficos
Autores principales: Kim, J-T, Lee, S-J, Kang, M A, Park, J E, Kim, B-Y, Yoon, D-Y, Yang, Y, Lee, C-H, Yeom, Y I, Choe, Y-K, Lee, H G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877556/
https://www.ncbi.nlm.nih.gov/pubmed/24357805
http://dx.doi.org/10.1038/cddis.2013.485