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Dysregulated microRNAs in amyotrophic lateral sclerosis microglia modulate genes linked to neuroinflammation

MicroRNAs (miRNAs) regulate gene expression at post-transcriptional level and are key modulators of immune system, whose dysfunction contributes to the progression of neuroinflammatory diseaseas such as amyotrophic lateral sclerosis (ALS), the most widespread motor neuron disorder. ALS is a non-cell...

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Detalles Bibliográficos
Autores principales: Parisi, C, Arisi, I, D'Ambrosi, N, Storti, A E, Brandi, R, D'Onofrio, M, Volonté, C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877562/
https://www.ncbi.nlm.nih.gov/pubmed/24336079
http://dx.doi.org/10.1038/cddis.2013.491