PATZ1 interacts with p53 and regulates expression of p53-target genes enhancing apoptosis or cell survival based on the cellular context

PATZ1 is a transcriptional factor functioning either as an activator or a repressor of gene transcription depending upon the cellular context. It appears to have a dual oncogenic/anti-oncogenic activity. Indeed, it is overexpressed in colon carcinomas, and its silencing inhibits colon cancer cell pr...

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Detalles Bibliográficos
Autores principales: Valentino, T, Palmieri, D, Vitiello, M, Pierantoni, G M, Fusco, A, Fedele, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877567/
https://www.ncbi.nlm.nih.gov/pubmed/24336083
http://dx.doi.org/10.1038/cddis.2013.500

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877567/
https://www.ncbi.nlm.nih.gov/pubmed/24336083
http://dx.doi.org/10.1038/cddis.2013.500

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