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Oligomeric amyloid β induces IL-1β processing via production of ROS: implication in Alzheimer's disease

Alzheimer's disease (AD) is a chronic neurodegenerative disease characterized by progressive neuronal loss and cognitive decline. Oligomeric amyloid β (oAβ) is involved in the pathogenesis of AD by affecting synaptic plasticity and inhibiting long-term potentiation. Although several lines of ev...

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Detalles Bibliográficos
Autores principales: Parajuli, B, Sonobe, Y, Horiuchi, H, Takeuchi, H, Mizuno, T, Suzumura, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877570/
https://www.ncbi.nlm.nih.gov/pubmed/24357806
http://dx.doi.org/10.1038/cddis.2013.503