Cargando…
Oligomeric amyloid β induces IL-1β processing via production of ROS: implication in Alzheimer's disease
Alzheimer's disease (AD) is a chronic neurodegenerative disease characterized by progressive neuronal loss and cognitive decline. Oligomeric amyloid β (oAβ) is involved in the pathogenesis of AD by affecting synaptic plasticity and inhibiting long-term potentiation. Although several lines of ev...
Autores principales: | Parajuli, B, Sonobe, Y, Horiuchi, H, Takeuchi, H, Mizuno, T, Suzumura, A |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877570/ https://www.ncbi.nlm.nih.gov/pubmed/24357806 http://dx.doi.org/10.1038/cddis.2013.503 |
Ejemplares similares
-
Granulocyte-Colony Stimulating Factor Attenuates Oligomeric Amyloid β Neurotoxicity by Activation of Neprilysin
por: Doi, Yukiko, et al.
Publicado: (2014) -
Fingolimod Phosphate Attenuates Oligomeric Amyloid β–Induced Neurotoxicity via Increased Brain-Derived Neurotrophic Factor Expression in Neurons
por: Doi, Yukiko, et al.
Publicado: (2013) -
The neuroprotective effects of milk fat globule-EGF factor 8 against oligomeric amyloid β toxicity
por: Li, Endong, et al.
Publicado: (2012) -
Microglial phagocytosis induced by fibrillar β-amyloid is attenuated by oligomeric β-amyloid: implications for Alzheimer's disease
por: Pan, Xiao-dong, et al.
Publicado: (2011) -
Interleukin-1β Induces Blood–Brain Barrier Disruption by Downregulating Sonic Hedgehog in Astrocytes
por: Wang, Yue, et al.
Publicado: (2014)