N-Acetylcysteine Prevents Hypertension via Regulation of the ADMA-DDAH Pathway in Young Spontaneously Hypertensive Rats

Asymmetric dimethylarginine (ADMA) reduces nitric oxide (NO), thus causing hypertension. ADMA is metabolized by dimethylarginine dimethylaminohydrolase (DDAH), which can be inhibited by oxidative stress. N-Acetylcysteine (NAC), an antioxidant, can facilitate glutathione (GSH) synthesis. We aimed to...

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Detalles Bibliográficos
Autores principales: Fan, Nai-Chia, Tsai, Chih-Min, Hsu, Chien-Ning, Huang, Li-Tung, Tain, You-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877599/
https://www.ncbi.nlm.nih.gov/pubmed/24455716
http://dx.doi.org/10.1155/2013/696317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877599/
https://www.ncbi.nlm.nih.gov/pubmed/24455716
http://dx.doi.org/10.1155/2013/696317

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