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Evidence from Mouse and Man for a Role of Neuregulin 3 in Nicotine Dependence

Addiction to nicotine and ability to quit smoking are influenced by genetic factors. We used functional genomic approaches (chromatin immunoprecipitation (ChIP) and whole genome sequencing) to identify CREB targets following chronic nicotine administration and withdrawal in rodents. fWe found that c...

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Detalles Bibliográficos
Autores principales: Turner, Jill R., Ray, Riju, Lee, Bridgin, Everett, Logan, Xiang, Jing, Jepson, Christopher, Kaestner, Klaus H., Lerman, Caryn, Blendy, Julie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877725/
https://www.ncbi.nlm.nih.gov/pubmed/23999525
http://dx.doi.org/10.1038/mp.2013.104