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Multiple small RNA pathways regulate the silencing of repeated and foreign genes in C. elegans

Gene segments from other organisms, such as viruses, are detected as foreign and targeted for silencing by RNAi pathways. A deep-sequencing map of the small RNA response to repeated transgenes introduced to Caenorhabditis elegans revealed that specific segments are targeted by siRNAs. Silencing of t...

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Detalles Bibliográficos
Autores principales: Fischer, Sylvia E.J., Pan, Qi, Breen, Peter C., Qi, Yan, Shi, Zhen, Zhang, Chi, Ruvkun, Gary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877757/
https://www.ncbi.nlm.nih.gov/pubmed/24352423
http://dx.doi.org/10.1101/gad.233254.113