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Multiple small RNA pathways regulate the silencing of repeated and foreign genes in C. elegans
Gene segments from other organisms, such as viruses, are detected as foreign and targeted for silencing by RNAi pathways. A deep-sequencing map of the small RNA response to repeated transgenes introduced to Caenorhabditis elegans revealed that specific segments are targeted by siRNAs. Silencing of t...
Autores principales: | Fischer, Sylvia E.J., Pan, Qi, Breen, Peter C., Qi, Yan, Shi, Zhen, Zhang, Chi, Ruvkun, Gary |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877757/ https://www.ncbi.nlm.nih.gov/pubmed/24352423 http://dx.doi.org/10.1101/gad.233254.113 |
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