The cannabinoid receptor 1 associates with NMDA receptors to produce glutamatergic hypofunction: implications in psychosis and schizophrenia

The endocannabinoid system is widespread throughout the central nervous system and its type 1 receptor (CB1) plays a crucial role in preventing the neurotoxicity caused by activation of glutamate N-methyl-D-aspartate receptors (NMDARs). Indeed, it is the activity of NMDARs themselves that provides t...

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Detalles Bibliográficos
Autores principales: Sánchez-Blázquez, Pilar, Rodríguez-Muñoz, María, Garzón, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877778/
https://www.ncbi.nlm.nih.gov/pubmed/24427139
http://dx.doi.org/10.3389/fphar.2013.00169