Cargando…

Activation of the Nuclear Factor E2-Related Factor 2 Pathway by Novel Natural Products Halomadurones A–D and a Synthetic Analogue

Two novel chlorinated pyrones, halomadurones A and B, and two novel brominated analogues, halomadurones C and D, were isolated from a marine Actinomadura sp. cultivated from the ascidian Ecteinascidia turbinata. Additionally, a non-halogenated analogue, 2-methyl-6-((E)-3-methyl-1,3-hexadiene)-γ-pyro...

Descripción completa

Detalles Bibliográficos
Autores principales: Wyche, Thomas P., Standiford, Miranda, Hou, Yanpeng, Braun, Doug, Johnson, Delinda A., Johnson, Jeffrey A., Bugni, Tim S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877905/
https://www.ncbi.nlm.nih.gov/pubmed/24351907
http://dx.doi.org/10.3390/md11125089