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Polypeptide Modulators of TRPV1 Produce Analgesia without Hyperthermia

Transient receptor potential vanilloid 1 receptors (TRPV1) play a significant physiological role. The study of novel TRPV1 agonists and antagonists is essential. Here, we report on the characterization of polypeptide antagonists of TRPV1 based on in vitro and in vivo experiments. We evaluated the ab...

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Detalles Bibliográficos
Autores principales: Andreev, Yaroslav A., Kozlov, Sergey A., Korolkova, Yuliya V., Dyachenko, Igor A., Bondarenko, Dmitrii A., Skobtsov, Denis I., Murashev, Arkadii N., Kotova, Polina D., Rogachevskaja, Olga A., Kabanova, Natalia V., Kolesnikov, Stanislav S., Grishin, Eugene V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877906/
https://www.ncbi.nlm.nih.gov/pubmed/24351908
http://dx.doi.org/10.3390/md11125100