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Recent Updates on Acetaminophen Hepatotoxicity: The Role of Nrf2 in Hepatoprotection
Acetaminophen (APAP) known as paracetamol is the main ingredient in Tylenol, which has analgesic and anti-pyretic properties. Inappropriate use of APAP causes major morbidity and mortality secondary to hepatic failure. Overdose of APAP depletes the hepatic glutathione (GSH) rapidly, and the metaboli...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Korean Society of Toxicology
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877995/ https://www.ncbi.nlm.nih.gov/pubmed/24386516 http://dx.doi.org/10.5487/TR.2013.29.3.165 |