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Recent Updates on Acetaminophen Hepatotoxicity: The Role of Nrf2 in Hepatoprotection

Acetaminophen (APAP) known as paracetamol is the main ingredient in Tylenol, which has analgesic and anti-pyretic properties. Inappropriate use of APAP causes major morbidity and mortality secondary to hepatic failure. Overdose of APAP depletes the hepatic glutathione (GSH) rapidly, and the metaboli...

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Detalles Bibliográficos
Autores principales:	Gum, Sang Il, Cho, Min Kyung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Society of Toxicology 2013
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877995/ https://www.ncbi.nlm.nih.gov/pubmed/24386516 http://dx.doi.org/10.5487/TR.2013.29.3.165

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