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Development and Validation of a Liquid Chromatography-Tandem Mass Spectrometry Method for the Determination of ε-Acetamidocaproic Acid in Rat Plasma

A simple and rapid liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed and validated for the quantification of ε-acetamidocaproic acid (AACA), the primary metabolite of zinc acexamate (ZAC), in rat plasma by using normetanephrine as an internal standard. Sample preparation...

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Detalles Bibliográficos
Autores principales: Kim, Tae Hyun, Choi, Yong Seok, Choi, Young Hee, Kim, Yoon Gyoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Toxicology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878000/
https://www.ncbi.nlm.nih.gov/pubmed/24386521
http://dx.doi.org/10.5487/TR.2013.29.3.203