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Leptin modulates electrophysiological characteristics and isoproterenol-induced arrhythmogenesis in atrial myocytes
BACKGROUND: Obesity is an important risk factor for atrial fibrillation (AF). Leptin is an important adipokine. However, it is not clear whether leptin directly modulates the electrophysiological characteristics of atrial myocytes. RESULTS: Whole cell patch clamp and indo-1 fluorescence were used to...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878176/ https://www.ncbi.nlm.nih.gov/pubmed/24354396 http://dx.doi.org/10.1186/1423-0127-20-94 |