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Leptin modulates electrophysiological characteristics and isoproterenol-induced arrhythmogenesis in atrial myocytes

BACKGROUND: Obesity is an important risk factor for atrial fibrillation (AF). Leptin is an important adipokine. However, it is not clear whether leptin directly modulates the electrophysiological characteristics of atrial myocytes. RESULTS: Whole cell patch clamp and indo-1 fluorescence were used to...

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Detalles Bibliográficos
Autores principales: Lin, Yung-Kuo, Chen, Yao-Chang, Huang, Jen-Hung, Lin, Yenn-Jiang, Huang, Shiang-Suo, Chen, Shih-Ann, Chen, Yi-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878176/
https://www.ncbi.nlm.nih.gov/pubmed/24354396
http://dx.doi.org/10.1186/1423-0127-20-94