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Can too many copies spoil the broth?

The success of Pichia pastoris as a heterologous expression system lies predominantly in the impressive yields that can be achieved due to high volumetric productivity. However, low specific productivity still inhibits the potential success of this platform. Multi-(gene) copy clones are potentially...

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Detalles Bibliográficos
Autores principales: Aw, Rochelle, Polizzi, Karen M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878197/
https://www.ncbi.nlm.nih.gov/pubmed/24354594
http://dx.doi.org/10.1186/1475-2859-12-128