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Promoter methylation of Wnt-antagonists in polypoid and nonpolypoid colorectal adenomas

BACKGROUND: Nonpolypoid adenomas are a subgroup of colorectal adenomas that have been associated with a more aggressive clinical behaviour compared to their polypoid counterparts. A substantial proportion of nonpolypoid and polypoid adenomas lack APC mutations, APC methylation or chromosomal loss of...

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Detalles Bibliográficos
Autores principales: Voorham, Quirinus JM, Janssen, Jerry, Tijssen, Marianne, Snellenberg, Suzanne, Mongera, Sandra, van Grieken, Nicole CT, Grabsch, Heike, Kliment, Martin, Rembacken, Bjorn J, Mulder, Chris JJ, van Engeland, Manon, Meijer, Gerrit A, Steenbergen, Renske DM, Carvalho, Beatriz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878219/
https://www.ncbi.nlm.nih.gov/pubmed/24350795
http://dx.doi.org/10.1186/1471-2407-13-603