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Targeting the PDGF signaling pathway in tumor treatment
Platelet-derived growth factor (PDGF) isoforms and PDGF receptors have important functions in the regulation of growth and survival of certain cell types during embryonal development and e.g. tissue repair in the adult. Overactivity of PDGF receptor signaling, by overexpression or mutational events,...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878225/ https://www.ncbi.nlm.nih.gov/pubmed/24359404 http://dx.doi.org/10.1186/1478-811X-11-97 |