Network-based differential gene expression analysis suggests cell cycle related genes regulated by E2F1 underlie the molecular difference between smoker and non-smoker lung adenocarcinoma

BACKGROUND: Differential gene expression (DGE) analysis is commonly used to reveal the deregulated molecular mechanisms of complex diseases. However, traditional DGE analysis (e.g., the t test or the rank sum test) tests each gene independently without considering interactions between them. Top-rank...

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Detalles Bibliográficos
Autores principales: Wu, Chao, Zhu, Jun, Zhang, Xuegong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878503/
https://www.ncbi.nlm.nih.gov/pubmed/24341432
http://dx.doi.org/10.1186/1471-2105-14-365

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878503/
https://www.ncbi.nlm.nih.gov/pubmed/24341432
http://dx.doi.org/10.1186/1471-2105-14-365

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