Naturally occurring resistance mutations to inhibitors of HCV NS5A region and NS5B polymerase in DAA treatment-naïve patients

BACKGROUND: Direct-acting antiviral (DAA) agents target HCV proteins; some of these have already been approved for the treatment of HCV infection, while others are in development. However, selection of DAA-resistant viral variants may hamper treatment. The aim of this study was to illustrate potenti...

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Detalles Bibliográficos
Autores principales: Paolucci, Stefania, Fiorina, Loretta, Mariani, Bianca, Gulminetti, Roberto, Novati, Stefano, Barbarini, Giorgio, Bruno, Raffaele, Baldanti, Fausto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878512/
https://www.ncbi.nlm.nih.gov/pubmed/24341898
http://dx.doi.org/10.1186/1743-422X-10-355

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878512/
https://www.ncbi.nlm.nih.gov/pubmed/24341898
http://dx.doi.org/10.1186/1743-422X-10-355

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