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Asymmetric cyclopropanation of chalcones using chiral phase-transfer catalysts
The first phase-transfer catalyzed cyclopropanation reaction of chalcones using bromomalonates as the nucleophiles in a Michael Initiated Ring Closing reaction (MIRC) was developed. Key to success was the use of a free OH-containing cinchona alkaloid ammonium salt catalyst and carefully optimized li...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878557/ https://www.ncbi.nlm.nih.gov/pubmed/24391288 http://dx.doi.org/10.1016/j.tetlet.2013.02.095 |