Dynamic Analysis of Gene Expression and Genome-wide Transcription Factor Binding during Lineage Specification of Multipotent Progenitors

We used the paradigmatic GATA-PU.1 axis to explore, at the systems level, dynamic relationships between transcription factor (TF) binding and global gene expression programs as multipotent cells differentiate. We combined global ChIP-seq of GATA1, GATA2, and PU.1 with expression profiling during dif...

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Detalles Bibliográficos
Autores principales: May, Gillian, Soneji, Shamit, Tipping, Alex J., Teles, Jose, McGowan, Simon J., Wu, Mengchu, Guo, Yanping, Fugazza, Cristina, Brown, John, Karlsson, Göran, Pina, Cristina, Olariu, Victor, Taylor, Stephen, Tenen, Daniel G., Peterson, Carsten, Enver, Tariq
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2013
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878573/
https://www.ncbi.nlm.nih.gov/pubmed/24120743
http://dx.doi.org/10.1016/j.stem.2013.09.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878573/
https://www.ncbi.nlm.nih.gov/pubmed/24120743
http://dx.doi.org/10.1016/j.stem.2013.09.003

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