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Exposure to vehicle emissions results in altered blood brain barrier permeability and expression of matrix metalloproteinases and tight junction proteins in mice

BACKGROUND: Traffic-generated air pollution-exposure is associated with adverse effects in the central nervous system (CNS) in both human exposures and animal models, including neuroinflammation and neurodegeneration. While alterations in the blood brain barrier (BBB) have been implicated as a poten...

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Detalles Bibliográficos
Autores principales: Oppenheim, Hannah A, Lucero, JoAnn, Guyot, Anne-Cécile, Herbert, Lindsay M, McDonald, Jacob D, Mabondzo, Aloïse, Lund, Amie K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878624/
https://www.ncbi.nlm.nih.gov/pubmed/24344990
http://dx.doi.org/10.1186/1743-8977-10-62