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A flexible statistical model for alignment of label-free proteomics data – incorporating ion mobility and product ion information

BACKGROUND: The goal of many proteomics experiments is to determine the abundance of proteins in biological samples, and the variation thereof in various physiological conditions. High-throughput quantitative proteomics, specifically label-free LC-MS/MS, allows rapid measurement of thousands of prot...

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Detalles Bibliográficos
Autores principales: Benjamin, Ashlee M, Thompson, J Will, Soderblom, Erik J, Geromanos, Scott J, Henao, Ricardo, Kraus, Virginia B, Moseley, M Arthur, Lucas, Joseph E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878627/
https://www.ncbi.nlm.nih.gov/pubmed/24341404
http://dx.doi.org/10.1186/1471-2105-14-364