Epigenetic silencing of glutaminase 2 in human liver and colon cancers

BACKGROUND: Glutaminase 2 (Gls2) is a p53 target gene and is known to play an important role in energy metabolism. Gls2 has been reported to be downregulated in human hepatocellular carcinomas (HCC). However, the underlying mechanism responsible for its downregulation is still unclear. Here, we inve...

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Detalles Bibliográficos
Autores principales: Zhang, Jianbin, Wang, Cheng, Chen, Mingquan, Cao, Jianping, Zhong, Ying, Chen, Liting, Shen, Han-Ming, Xia, Dajing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878668/
https://www.ncbi.nlm.nih.gov/pubmed/24330717
http://dx.doi.org/10.1186/1471-2407-13-601

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878668/
https://www.ncbi.nlm.nih.gov/pubmed/24330717
http://dx.doi.org/10.1186/1471-2407-13-601

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