High epiregulin expression in human U87 glioma cells relies on IRE1α and promotes autocrine growth through EGF receptor

BACKGROUND: Epidermal growth factor (EGF) receptors contribute to the development of malignant glioma. Here we considered the possible implication of the EGFR ligand epiregulin (EREG) in glioma development in relation to the activity of the unfolded protein response (UPR) sensor IRE1α. We also exami...

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Detalles Bibliográficos
Autores principales: Auf, Gregor, Jabouille, Arnaud, Delugin, Maylis, Guérit, Sylvaine, Pineau, Raphael, North, Sophie, Platonova, Natalia, Maitre, Marlène, Favereaux, Alexandre, Vajkoczy, Peter, Seno, Masaharu, Bikfalvi, Andreas, Minchenko, Dmitri, Minchenko, Oleksandr, Moenner, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878670/
https://www.ncbi.nlm.nih.gov/pubmed/24330607
http://dx.doi.org/10.1186/1471-2407-13-597

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878670/
https://www.ncbi.nlm.nih.gov/pubmed/24330607
http://dx.doi.org/10.1186/1471-2407-13-597

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