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High epiregulin expression in human U87 glioma cells relies on IRE1α and promotes autocrine growth through EGF receptor
BACKGROUND: Epidermal growth factor (EGF) receptors contribute to the development of malignant glioma. Here we considered the possible implication of the EGFR ligand epiregulin (EREG) in glioma development in relation to the activity of the unfolded protein response (UPR) sensor IRE1α. We also exami...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878670/ https://www.ncbi.nlm.nih.gov/pubmed/24330607 http://dx.doi.org/10.1186/1471-2407-13-597 |