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The prognostic values of EGFR expression and KRAS mutation in patients with synchronous or metachronous metastatic colorectal cancer

BACKGROUND: The epidermal growth factor receptor (EGFR)/RAS/RAF/MEK/MAPK pathway is an important pathway in the carcinogenesis, invasion and metastasis of colorectal cancers (CRCs). We conducted a retrospective study to determine the prognostic values of EGFR expression and KRAS mutation in patients...

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Detalles Bibliográficos
Autores principales: Huang, Ching-Wen, Tsai, Hsiang-Lin, Chen, Yi-Ting, Huang, Chun-Ming, Ma, Cheng-Jen, Lu, Chien-Yu, Kuo, Chao-Hung, Wu, Deng-Chyang, Chai, Chee-Yin, Wang, Jaw-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878756/
https://www.ncbi.nlm.nih.gov/pubmed/24330663
http://dx.doi.org/10.1186/1471-2407-13-599