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Structural and functional evidence for a substrate exclusion mechanism in mammalian tolloid like-1 (TLL-1) proteinase

Bone morphogenetic protein-1 (BMP-1)/tolloid proteinases are fundamental to regulating dorsal ventral patterning and extracellular matrix deposition. In mammals there are four proteinases, the splice variants BMP-1 and mammalian tolloid (mTLD), and tolloid like-1 and -2 (TLL-1/2). BMP-1 has the high...

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Detalles Bibliográficos
Autores principales: Berry, Richard, Jowitt, Thomas A., Garrigue-Antar, Laure, Kadler, Karl E., Baldock, Clair
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science B.V 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878766/
https://www.ncbi.nlm.nih.gov/pubmed/20043912
http://dx.doi.org/10.1016/j.febslet.2009.12.050