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Synthesis and biological characterisation of (18)F-SIG343 and (18)F-SIG353, novel and high selectivity σ(2) radiotracers, for tumour imaging properties
BACKGROUND: Sigma2 (σ(2)) receptors are highly expressed in cancer cell lines and in tumours. Two novel selective (18)F-phthalimido σ(2) ligands, (18)F-SIG343 and (18)F-SIG353, were prepared and characterised for their potential tumour imaging properties. METHODS: Preparation of (18)F-SIG343 and (18...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878827/ https://www.ncbi.nlm.nih.gov/pubmed/24330526 http://dx.doi.org/10.1186/2191-219X-3-80 |