Synthesis and biological characterisation of (18)F-SIG343 and (18)F-SIG353, novel and high selectivity σ(2) radiotracers, for tumour imaging properties

BACKGROUND: Sigma2 (σ(2)) receptors are highly expressed in cancer cell lines and in tumours. Two novel selective (18)F-phthalimido σ(2) ligands, (18)F-SIG343 and (18)F-SIG353, were prepared and characterised for their potential tumour imaging properties. METHODS: Preparation of (18)F-SIG343 and (18...

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Detalles Bibliográficos
Autores principales: Nguyen, Vu H, Pham, Tien, Fookes, Chris, Berghofer, Paula, Greguric, Ivan, Arthur, Andrew, Mattner, Filomena, Rahardjo, Gita, Davis, Emma, Howell, Nicholas, Gregoire, Marie-Claude, Katsifis, Andrew, Shepherd, Rachael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878827/
https://www.ncbi.nlm.nih.gov/pubmed/24330526
http://dx.doi.org/10.1186/2191-219X-3-80

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