Effects of 17-allylamino-17-demethoxygeldanamycin (17-AAG) in transgenic mouse models of frontotemporal lobar degeneration and Alzheimer’s disease

Alzheimer’s disease (AD), the most common dementia, is characterized by potentially neurotoxic aggregation of Aβ peptide and tau protein, and their deposition as amyloid plaques and neurofibrillary tangles (NFTs). Tau aggregation also occurs in other common neurodegenerative diseases. Frontotemporal...

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Detalles Bibliográficos
Autores principales: Ho, Shuk Wai, Tsui, Yuk Tung Chanel, Wong, Ting Ting, Cheung, Stanley Kwok-Kuen, Goggins, William B, Yi, Lau Ming, Cheng, Kwok Kin, Baum, Larry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878847/
https://www.ncbi.nlm.nih.gov/pubmed/24344631
http://dx.doi.org/10.1186/2047-9158-2-24

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878847/
https://www.ncbi.nlm.nih.gov/pubmed/24344631
http://dx.doi.org/10.1186/2047-9158-2-24

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