HIV integration and T cell death: additional commentary

Estaquier et al. provide commentary on our paper that elucidated the mechanism by which HIV-1 causes cell death in activated CD4 T lymphocytes. We showed that proviral DNA integration triggers DNA-PK dependent death signaling, leading to p53 phosphorylation and cell demise (Cooper A et al. Nature498...

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Detalles Bibliográficos
Autores principales: Cooper, Arik, García, Mayra, Petrovas, Constantinos, Yamamoto, Takuya, Koup, Richard A, Nabel, Gary J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878915/
https://www.ncbi.nlm.nih.gov/pubmed/24321564
http://dx.doi.org/10.1186/1742-4690-10-150

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878915/
https://www.ncbi.nlm.nih.gov/pubmed/24321564
http://dx.doi.org/10.1186/1742-4690-10-150

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