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Enhanced membrane protein expression by engineering increased intracellular membrane production

BACKGROUND: Membrane protein research is frequently hampered by the low natural abundance of these proteins in cells and typically relies on recombinant gene expression. Different expression systems, like mammalian cells, insect cells, bacteria and yeast are being used, but very few research efforts...

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Detalles Bibliográficos
Autores principales: Guerfal, Mouna, Claes, Katrien, Knittelfelder, Oskar, De Rycke, Riet, Kohlwein, Sepp D, Callewaert, Nico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878919/
https://www.ncbi.nlm.nih.gov/pubmed/24321035
http://dx.doi.org/10.1186/1475-2859-12-122