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Evaluation of infectious titer in a candidate HSV type 2 vaccine by a quantitative molecular approach
BACKGROUND: One of the critical tasks in analytical testing is to monitor and assign the infectivity or potency of viral based vaccines from process development to production of final clinical lots. In this study, a high throughput RT-qPCR based approach was developed to evaluate the infectious titr...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878963/ https://www.ncbi.nlm.nih.gov/pubmed/24313978 http://dx.doi.org/10.1186/1471-2180-13-284 |