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Evaluation of infectious titer in a candidate HSV type 2 vaccine by a quantitative molecular approach

BACKGROUND: One of the critical tasks in analytical testing is to monitor and assign the infectivity or potency of viral based vaccines from process development to production of final clinical lots. In this study, a high throughput RT-qPCR based approach was developed to evaluate the infectious titr...

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Detalles Bibliográficos
Autores principales: Azizi, Ali, Tang, Mei, Gisonni-Lex, Lucy, Mallet, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878963/
https://www.ncbi.nlm.nih.gov/pubmed/24313978
http://dx.doi.org/10.1186/1471-2180-13-284