Synthesis and biological evaluation of Combretastatin A-4 derivatives containing a 3’-O-substituted carbonic ether moiety as potential antitumor agents

BACKGROUND: Combretastatin A-4 (CA-4), which is an excellent antineoplastic agent, was isolated from Combretum caffrum. To date, structural modification studies of CA-4 have focused predominantly on the construction of new therapeutic agents for drug discovery. As a part of our ongoing work towards...

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Detalles Bibliográficos
Autores principales: Ma, Mingyi, Sun, Longru, Lou, Hongxiang, Ji, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878987/
https://www.ncbi.nlm.nih.gov/pubmed/24304592
http://dx.doi.org/10.1186/1752-153X-7-179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878987/
https://www.ncbi.nlm.nih.gov/pubmed/24304592
http://dx.doi.org/10.1186/1752-153X-7-179

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