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Loss of MEF2D expression inhibits differentiation and contributes to oncogenesis in rhabdomyosarcoma cells

BACKGROUND: Rhabdomyosarcoma (RMS) is a highly malignant pediatric cancer that is the most common form of soft tissue tumors in children. RMS cells have many features of skeletal muscle cells, yet do not differentiate. Thus, our studies have focused on the defects present in these cells that block m...

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Detalles Bibliográficos
Autores principales: Zhang, Meiling, Truscott, Jamie, Davie, Judith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879063/
https://www.ncbi.nlm.nih.gov/pubmed/24279793
http://dx.doi.org/10.1186/1476-4598-12-150